Changes in alanine aminotransferase in adults with severe and complicated obesity during a milk-based meal replacement programme.
Razk AbdalgwadMohammed Faraz RafeyConor MurphyIulia IoanaPaula Mary O'SheaEoin SlatteryColin DavenportDerek Timothy O'KeeffeFrancis Martin FinucanePublished in: Nutrition & metabolism (2020)
In adults with severe and complicated obesity undergoing a milk-based meal replacement programme, there was an initial unanticipated rise in ALT in the first 2 weeks, followed by a gradual overall reduction by 24 weeks. These findings suggest that rapid weight loss secondary to significant caloric restriction might induce a transient deterioration in hepatic steatosis prior to an ultimate overall improvement.
Keyphrases
- weight loss
- bariatric surgery
- roux en y gastric bypass
- insulin resistance
- metabolic syndrome
- gastric bypass
- weight gain
- early onset
- high fat diet induced
- study protocol
- type diabetes
- gestational age
- body mass index
- glycemic control
- obese patients
- randomized controlled trial
- cerebral ischemia
- adipose tissue
- brain injury
- sensitive detection
- loop mediated isothermal amplification