Examination of exclusion criteria in total knee arthroplasty rehabilitation trials: influence on the application of evidence in day-to-day practice.
Andrew J KittelsonBrian J LoydJeremy GraberMichael A HimawanDawn WaughJacqueline DavenportThomas J HoogeboomJennifer Stevens-LapsleyPublished in: Journal of evaluation in clinical practice (2021)
Many patients in the clinical dataset were "ineligible" for research participation based upon common TKA rehabilitation trial exclusion criteria. However, the postoperative recovery rate did not differ between "eligible" and "ineligible" groups based on individual exclusion criterion-except for individuals with diabetes. This suggests that both clinical and research populations may recover similarly from TKA.
Keyphrases
- total knee arthroplasty
- total hip
- end stage renal disease
- chronic kidney disease
- ejection fraction
- type diabetes
- newly diagnosed
- cardiovascular disease
- healthcare
- clinical trial
- primary care
- physical activity
- study protocol
- patients undergoing
- prognostic factors
- randomized controlled trial
- metabolic syndrome
- adipose tissue
- genetic diversity
- insulin resistance