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Synergistic Adhesiveness of Fibronectin with PHSRN Peptide in Gelatin Mixture Promotes the Therapeutic Potential of Human ES-Derived MSCs.

Hye-Seon KimSung Hyun ChoiMi-Lan KangKi-Won LeeKi Nam KimHak-Joon Sung
Published in: Cellular and molecular bioengineering (2019)
This study suggests a potential solution by promoting the surface affinity of culture plates using a mixture of human fibronectin and its adjuvant PHSRN peptide in gelatin. The FNGP plate is expected to serve as an effective alternative for serum-free MSC expansion for bench to clinical transition.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • mesenchymal stem cells
  • hyaluronic acid
  • bone regeneration
  • cancer therapy
  • tissue engineering