Grading and outcome prediction of pediatric diffuse astrocytic tumors with diffusion and arterial spin labeling perfusion MRI in comparison with 18F-DOPA PET.
Giovanni MoranaArnoldo PiccardoDomenico TortoraMatteo PuntoniMariasavina SeverinoPaolo NozzaMarcello RavegnaniAlessandro ConsalesSamantha MascelliAlessandro RasoManlio CabriaAntonio VerricoClaudia MilanaccioAndrea RossiPublished in: European journal of nuclear medicine and molecular imaging (2017)
DWI, ASL and 18F-DOPA PET provide useful complementary information for pediatric DAT grading. 18F-DOPA uptake better correlates with PFS prediction. Combining MRI and PET data provides the highest predictive power for prognosticating tumor progression suggesting a synergistic role of these diagnostic tools.
Keyphrases
- contrast enhanced
- computed tomography
- diffusion weighted imaging
- pet ct
- positron emission tomography
- diffusion weighted
- magnetic resonance imaging
- pet imaging
- magnetic resonance
- poor prognosis
- low grade
- room temperature
- electronic health record
- density functional theory
- drug delivery
- cancer therapy
- artificial intelligence
- healthcare
- high grade
- deep learning