Superovulation alters the expression of endometrial genes critical to tissue remodeling and placentation.

Suneeta SenapatiFan WangTeri OrdChristos CoutifarisRui FengMonica A Mainigi

Published in: Journal of assisted reproduction and genetics (2018)

Superovulation alters expression of genes critical to endometrial remodeling during early implantation. Such changes could lead to altered trophoblast migration and impaired endovascular invasion. These findings offer a potential mechanism for the adverse perinatal outcomes observed following embryo transfer during fresh IVF cycles.

Keyphrases

poor prognosis
genome wide
pregnant women
endometrial cancer
binding protein
genome wide identification
bioinformatics analysis
long non coding rna
cell migration
emergency department
gene expression
metabolic syndrome
skeletal muscle
adipose tissue
transcription factor
drug induced