Preoperative Assessment of Medication-Related Osteonecrosis of the Jaw Using [18F]fluoride Positron Emission Tomography (PET)/CT and [18F]fluorodeoxyglucose PET/MRI in Correlation with Histomorphometry and Micro-CT-A Prospective Comparative Study.
Christian Philipp ReinertChristina PfannenbergBrigitte GückelHelmut DittmannChristian Peter la FougèreKonstantin NikolaouSiegmar ReinertRouven SchönhofSebastian HoefertPublished in: Diagnostics (Basel, Switzerland) (2024)
In summary, [18F]fluoride PET accurately identified MRONJ extent, revealing functional changes in jawbone remodeling not visible on CT. [18F]FDG PET showed differences in bone and soft tissue, though less pronounced. This method aids in evaluating disease activity and guiding treatment planning, requiring further research for optimal surgical approaches based on tracer uptake.
Keyphrases
- positron emission tomography
- pet ct
- disease activity
- computed tomography
- soft tissue
- systemic lupus erythematosus
- rheumatoid arthritis
- contrast enhanced
- pet imaging
- rheumatoid arthritis patients
- magnetic resonance imaging
- ankylosing spondylitis
- drinking water
- dual energy
- healthcare
- juvenile idiopathic arthritis
- patients undergoing
- bone mineral density
- emergency department
- antiretroviral therapy
- body composition
- adverse drug