A systematic review of genetic mutations in pulmonary arterial hypertension.
Gerardo Garcia-RivasCarlos Jerjes-SánchezDavid RodriguezJosé Garcia-PelaezVíctor Treviño-AlvaradoPublished in: BMC medical genetics (2017)
Our systematic review proposes an expanded gene panel for more accurate characterization of the genetic incidence and risk in PAH. Their usage would increase the knowledge of PAH in terms of genetic counseling, early diagnosis, and potential prognosis of the disease.
Keyphrases
- pulmonary arterial hypertension
- genome wide
- systematic review
- copy number
- pulmonary artery
- pulmonary hypertension
- healthcare
- dna methylation
- meta analyses
- high resolution
- randomized controlled trial
- polycyclic aromatic hydrocarbons
- gene expression
- transcription factor
- hepatitis c virus
- human immunodeficiency virus
- hiv infected
- genome wide identification