Racial differences in survival and response to therapy in patients with metastatic colorectal cancer: A secondary analysis of CALGB/SWOG 80405 (Alliance A151931).
Rebecca A SnyderJun HeJennifer G Le-RademacherFang-Shu OuAndrew B DodgeTyler J ZemlaElectra D PaskettGeorge J ChangFederico InnocentiCharles BlankeHeinz-Josef LenzBlasé N PoliteAlan P VenookPublished in: Cancer (2021)
Despite improvements in screening and treatment, studies have demonstrated worse outcomes in Black patients with colorectal cancer. The purpose of this study was to determine whether there was a difference in cancer-specific outcomes among Black and White patients receiving equivalent treatment on the CALGB/SWOG 80405 randomized clinical trial. In this study, there was no difference in overall survival, progression-free survival, or response to therapy between Black and White patients treated on a clinical trial. These findings suggest that access to care and differences in treatment may be responsible for racial disparities in colorectal cancer.
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