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Myeloid malignancies with 5q and 7q deletions are associated with extreme genomic complexity, biallelic TP53 variants, and very poor prognosis.

Beth A PitelNeeraj SharmaCinthya Zepeda-MendozaJames B SmadbeckKathryn E PearceJoselle M CookGeorge VasmatzisZohar SachsRashmi Kanagal-ShamanaDavid ViswanathaSheng XiaoRobert B JenkinsXinjie XuNicole L HoppmanRhett P KetterlingJess F PetersonPatricia T GreippLinda B Baughn
Published in: Blood cancer journal (2021)
Keyphrases
  • poor prognosis
  • copy number
  • long non coding rna
  • intellectual disability
  • dendritic cells
  • bone marrow
  • acute myeloid leukemia
  • climate change
  • genome wide
  • dna methylation