Long-term outcomes of acute severe ulcerative colitis in the rescue therapy era: A multicentre cohort study.
Stefano FestaMaria Lia ScribanoDaniela PuglieseCristina BezzioMariabeatrice PrincipiDavide Giuseppe RibaldoneMariangela AlloccaGiammarco MocciGiorgia BodiniRocco SpagnuoloPiero VerniaSilvia MazzuoliFrancesco CostaBrigida BarberioRocco CosintinoGiulia ZerboniAnnalisa AratariAlessandro ArmuzziClaudio PapiPublished in: United European gastroenterology journal (2021)
Patients with acute severe ulcerative colitis avoiding early colectomy are at risk of long-term colectomy, especially if previously exposed to antitumour necrosis factor-α agents or if rescue therapy during the acute attack was required because of steroid refractoriness.