Expression of the DNA repair gene MLH1 correlates with survival in patients who have resected pancreatic cancer and have received adjuvant chemoradiation: NRG Oncology RTOG Study 9704.
Yaacov R LawrenceJennifer MoughanAnthony M MaglioccoAlexander C KlimowiczWilliam F RegineRex B MowatThomas A DiPetrilloWilliam SmallJeffry P SimkoTalia GolanKathryn A WinterChandan GuhaChristopher H CraneAdam P DickerPublished in: Cancer (2017)
In the current sample, MLH1 expression was correlated with long-term survival. Further studies should assess whether MLH1 expression predicts which patients with localized pancreatic cancer may benefit most from aggressive, multimodality treatment. Cancer 2018;124:491-8. © 2017 American Cancer Society.