Vaginal dinoprostone versus placebo for pain relief during intrauterine device insertion: a systematic review and meta-analysis of randomised controlled trials.

Ahmed Abu-Zaid Majed Saeed AlshahraniNisreen A AlbezrahNajlaa T MiskiMohammed AbuzaidSaud A AboudiAhlam BaredwanNada AlmadhiAfnan BaradwanOsama AlomarHany SalemIsmail A Al-BadawiSaeed Baradwan

Published in: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception (2021)

This first ever meta-analysis advocates that dinoprostone compared with placebo is safe, effective, and yields favourable analgesic outcomes during IUD insertion.

Keyphrases

systematic review
neuropathic pain
double blind
chronic pain
phase iii
meta analyses
pain management
spinal cord injury
spinal cord
anti inflammatory
clinical trial
randomized controlled trial
skeletal muscle
type diabetes
adipose tissue
metabolic syndrome
open label
study protocol