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Effect of Hyperthermic Intraperitoneal Chemotherapy on Cytoreductive Surgery in Gastric Cancer With Synchronous Peritoneal Metastases: The Phase III GASTRIPEC-I Trial.

Beate RauHauke LangAlfred KoenigsrainerInes GockelHorst-Guenter RauHendrik SeeligerChristian LerchenmuellerDaniel ReimRoger WahbaMartin AngeleSteffen HeegTobias KeckArved WeimannStefan ToppPompiliu PisoAndreas BrandlSilke SchuelePeter JoJohann PratschkeSandra WegelAlexander RehdersNicolas MoosmannJochen GaedckeVolker HeinemannEvelyn TripsMarkus LoefflerPeter Michael SchlagPeter C Thuss-Patience
Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
This study showed no OS difference between CRS + H and CRS-A. PFS and MFS were significantly better in the CRS + H group, which needs further exploration. HIPEC did not increase AEs.
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