PK-guided personalized prophylaxis with Nuwiq® (human-cl rhFVIII) in adults with severe haemophilia A.

T LissitchkovL RusenP GeorgievJerzy WindygaR KlamrothL GerchevaL NemesAndreas TiedeJ BichlerS KnaubL BelyanskayaO WalterK J Pasi

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2017)

PK-guided personalized prophylaxis with Nuwiq® provided bleeding protection and enabled the dosing interval to be extended to twice weekly or less in many patients and an overall dose reduction.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
early onset
induced pluripotent stem cells
pluripotent stem cells