Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of patient-derived liver organoids.
Yongqin YeVincent Chi Hang LuiRosana Ottakandathil BabuZhongluan WuWeifang WuPatrick Ho Yu ChungKenneth Kak Yuen WongBin WangPaul Kwong Hang TamPublished in: PloS one (2023)
The study identified dysregulated genes related to cancer pathways in CC patients suggesting cancer risk. The findings suggest that the elevated expression of FGFR2 and CEBPB in liver may contribute to cancer development in CC patients.