Monitoring Substantia Nigra Degeneration Using Free Water Imaging across Prodromal and Clinical Parkinson's Disease.

Gaiyan Zhou Jingru RenDanyan RongHao ZhouHouxu NingHui WangChenxi PanYajie WangRonggui ZhangZhiying GuoPeiyu HuangWeiguo Liu

Published in: Movement disorders : official journal of the Movement Disorder Society (2023)

The PSN free water increased from prodromal to early clinical stages, but the trend might be reversed in late disease stages. This biphasic trend should be considered when applying this marker in future studies. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

parkinson disease
high resolution
randomized controlled trial
systematic review
current status
case control
deep brain stimulation