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Harnessing the Power of CAR-NK Cells: A Promising Off-the-Shelf Therapeutic Strategy for CD38-Positive Malignancies.

Maryam AsadiRazie KianiVahid RazbanSeyed Nooreddin FarajiAmirhossein AhmadiJafar FallahiAmin RamezaniNasrollah Erfani
Published in: Iranian journal of immunology : IJI (2023)
The in vitro findings indicated that the anti-CD38 CAR-NK cells have the potential to be used as an off-the-shelf therapeutic strategy against CD38-positive malignancies. It is recommended that the present engineered NK cells undergo additional preclinical investigations before they can be considered for subsequent clinical trial studies.
Keyphrases
  • nk cells
  • clinical trial
  • randomized controlled trial
  • stem cells
  • study protocol
  • machine learning
  • risk assessment
  • cell therapy
  • climate change
  • double blind