Feasibility study on pre or postoperative accelerated radiotherapy (POP-ART) in breast cancer patients.

Hans Van HulleVincent VakaetGiselle PostAnnick Van GrevelingChris MontenAn HendrixKoen Van de VijverJo Van DorpePieter De VisschereGeert BraemsKatrien VandecasteeleHannelore DenysWilfried De NeveLiv Veldeman

Published in: Pilot and feasibility studies (2020)

The primary objective of the trial is to investigate the feasibility of preop radiotherapy. Secondary objectives are to search for biomarkers of response and toxicity and identify the involved cell death mechanisms and the effect of preop breast radiotherapy on the in-situ immune micro-environment.

Keyphrases

early stage
locally advanced
cell death
radiation induced
radiation therapy
clinical trial
patients undergoing
study protocol
oxidative stress
rectal cancer
randomized controlled trial
squamous cell carcinoma
phase iii
cell proliferation
phase ii
signaling pathway
oxide nanoparticles