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Altered expression of microRNAs in the rat diaphragm in a model of ventilator-induced diaphragm dysfunction after controlled mechanical ventilation.

Pengcheng WangXianlong ZhouGang LiHaoli MaRuining LiuYan Zhao
Published in: BMC genomics (2021)
The current research supplied novel perspectives on miRNAs in the diaphragm, which may not only be implicated in diaphragm dysfunction pathogenesis but could also be considered as therapeutic targets in diaphragm dysfunction.
Keyphrases
  • mechanical ventilation
  • acute respiratory distress syndrome
  • intensive care unit
  • oxidative stress
  • respiratory failure
  • extracorporeal membrane oxygenation
  • poor prognosis
  • drug induced
  • endothelial cells