Human dyskerin binds to cytoplasmic H/ACA-box-containing transcripts affecting nuclear hormone receptor dependence.

Federico ZacchiniGiulia VenturiVeronica De SanctisRoberto BertorelliClaudio CeccarelliDonatella SantiniMario TaffurelliMarianna PenzoDavide TreréAlberto IngaErik DassiLorenzo Montanaro

Published in: Genome biology (2022)

Our work suggests a cytoplasmic function for dyskerin which could affect mRNA post-transcriptional networks relevant for nuclear hormone receptor functions.

Keyphrases

transcription factor
endothelial cells
binding protein
induced pluripotent stem cells
pluripotent stem cells
healthcare