Depression, anxiety, and the risk of cancer: An individual participant data meta-analysis.
Lonneke A van TuijlMaartje BastenKuan-Yu PanRoel VermeulenLützen PortengenAlexander de GraeffJoost DekkerMirjam I GeerlingsAdriaan HoogendoornFemke LamersAdri C VoogdJessica AbellPhilip AwadallaAartjan T F BeekmanOttar BjerkesetAndy BoydYunsong CuiPhilipp FrankHenrike GalenkampBert GarssenSean HellingmanMartijn HuismanAnke HussTrynke R de JongMelanie R KeatsAlmar A L KokSteinar KrokstadFlora E van LeeuwenAnnemarie I LuikNolwenn NoiselN Charlotte Onland-MoretYves PayetteBrenda W J H PenninxIna RissanenAnnelieke M RoestRikje RuiterRobert A SchoeversDavid SoaveMandy SpaanAndrew SteptoeKarien StronksErik R SundEllen SweeneyEmma L TwaitAlison TeyhanW M Monique VerschurenKimberly D van der WillikJudith G M RosmalenAdelita V RanchorPublished in: Cancer (2023)
Depression and anxiety are not related to increased risk for most cancer outcomes, except for lung and smoking-related cancers. This study shows that key covariates are likely to explain the relationship between depression, anxiety, and lung and smoking-related cancers. PREREGISTRATION NUMBER: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=157677.
Keyphrases
- systematic review
- sleep quality
- papillary thyroid
- depressive symptoms
- squamous cell
- smoking cessation
- childhood cancer
- randomized controlled trial
- metabolic syndrome
- squamous cell carcinoma
- adipose tissue
- machine learning
- electronic health record
- skeletal muscle
- physical activity
- insulin resistance
- weight loss
- deep learning
- data analysis
- case control