Validation of ultrasound strategies to assess tumor extension and to predict high-risk endometrial cancer in women from the prospective IETA (International Endometrial Tumor Analysis)-4 cohort.
Jan Yvan Jos VerbakelF MasciliniL WynantsDaniela FischerovaA C TestaD FranchiF FrühaufD CibulaPelle G LindqvistR FruscioL A HaakG OpolskieneJuan Luis AlcazarV MaisJ W CarlsonPovilas SladkeviciusD TimmermanL ValentinT Van Den BoschElisabeth EpsteinPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2019)
In the hands of experienced ultrasound examiners, SA was superior to ultrasound measurements for the prediction of deep MI and CSI of endometrial cancer, especially in patients with a Grade-1 or -2 tumor. The mathematical models for the prediction of high-risk cancer performed as expected. The best strategies for predicting high-risk endometrial cancer were combining SA with biopsy grade and the subjective two-step strategy, both having an accuracy of 80%. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.