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Sex Hormones, Insulin, and Insulin-like Growth Factors in Recurrence of High-Stage Endometrial Cancer.

Melissa A MerrittHoward D StricklerAlan D HutsonMark H EinsteinThomas E RohanXiaonan XueMark E ShermanLouise A BrintonHerbert YuDavid Scott MillerNilsa C RamirezHeather A LankesMichael J BirrerGloria Shining HuangMarc J Gunter
Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2021)
This study may inform future clinical trials of endocrine-targeted adjuvant therapies in patients with endometrial cancer that could include baseline assessment of serum and tissue biomarkers of estradiol and insulin signaling pathways.
Keyphrases
  • endometrial cancer
  • type diabetes
  • clinical trial
  • glycemic control
  • signaling pathway
  • early stage
  • randomized controlled trial
  • epithelial mesenchymal transition
  • oxidative stress
  • drug delivery
  • phase ii