Liquiritin Alleviates Inflammation in Lipopolysaccharide-Induced Human Corneal Epithelial Cells.
Xian HeZiyang ZhangMeili HuXinyi LinXu WengJiajun LuLi FangXianhua ChenPublished in: Current eye research (2024)
Collectively, these findings imply that liquiritin suppresses the expression of proinflammatory cytokines, and the anti-inflammatory impacts of liquiritin may be caused by its repression of the Akt/NF-κB signaling pathway in LPS-induced HCECs. These data indicate that liquiritin could provide a potential therapeutic application for inflammation-associated corneal diseases.
Keyphrases
- lps induced
- inflammatory response
- signaling pathway
- lipopolysaccharide induced
- oxidative stress
- pi k akt
- anti inflammatory
- toll like receptor
- induced apoptosis
- endothelial cells
- epithelial mesenchymal transition
- poor prognosis
- optical coherence tomography
- cell proliferation
- wound healing
- electronic health record
- induced pluripotent stem cells
- cataract surgery
- immune response
- nuclear factor
- long non coding rna
- deep learning