Weekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial.

Paul S ThorntonAristides K ManiatisElena AghajanovaElena ChertokElpis VlachopapadopoulouZhengning LinWenjie SongEva Dam ChristoffersenVibeke Miller BreinholtTatiana KovalenkoElene GiorgadzeMaria Korpal-SzczyrskaPaul L HofmanDavid B KarpfAimee D ShuMichael Beckert

Published in: The Journal of clinical endocrinology and metabolism (2021)

The trial met its primary objective of noninferiority in AHV and further showed superiority of lonapegsomatropin compared to daily somatropin, with similar safety, in treatment-naïve children with GHD.

Keyphrases

young adults
growth hormone
clinical trial
study protocol
phase iii
body mass index
phase ii
randomized controlled trial
combination therapy
double blind
placebo controlled