Exosomal-miRNas expression and growth factors released by mononuclear cells of CLAD patients in response to extracorporeal photopheresis.
Sara BozziniEleonora BozzaCecilia BagneraClaudia Del FanteEugenio BaroneSimona De VitisMara De AmiciGiorgia TestaStefania CroceChiara ValsecchiMaria A AvanziniRosalia CacciatoreCristina MortellaroGianluca ViarengoCesare PerottiFederica MeloniPublished in: Journal of translational medicine (2024)
ECP might affect regulatory T cell functions, since both miR-142 and miR-146a have been shown to be involved in the regulation of suppressor regulatory T cell functions and DCs. On the other side ECP, possibly by regulating macrophage activation, is able to significantly down modulate CTGF release.
Keyphrases
- cell proliferation
- long non coding rna
- end stage renal disease
- poor prognosis
- long noncoding rna
- ejection fraction
- newly diagnosed
- induced apoptosis
- transcription factor
- chronic kidney disease
- prognostic factors
- adipose tissue
- peritoneal dialysis
- cell cycle arrest
- peripheral blood
- oxidative stress
- signaling pathway
- endoplasmic reticulum stress
- binding protein
- patient reported