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Cutaneous neurofibromas in Neurofibromatosis type I: a quantitative natural history study.

Ashley CannonMei-Jan ChenPeng LiKevin P BoydAmy TheosDavid T ReddenBruce Korf
Published in: Orphanet journal of rare diseases (2018)
The number and volume of cutaneous neurofibromas significantly increased over an 8-year timespan; however, the rate of increase is variable by individual and body region. These findings may provide insight into cutaneous neurofibroma development and benefit researchers considering clinical trials targeting cutaneous neurofibromas.
Keyphrases
  • clinical trial
  • high resolution
  • randomized controlled trial
  • drug delivery
  • mass spectrometry
  • phase ii
  • double blind