Catecholaminergic Modulation of Metacontrol is Reflected by Changes in Aperiodic EEG Activity.

Our findings suggest that the aperiodic exponent provides a neural marker of metacontrol states and changes therein. Further, we propose that the effectiveness of medications targeting catecholaminergic signaling can be evaluated by studying changes of cortical noise; fostering the idea of using the quantification of cortical noise as an indicator in pharmacological treatment.