Effects of resveratrol on VEGF & HIF1 genes expression in granulosa cells in the angiogenesis pathway and laboratory parameters of polycystic ovary syndrome: a triple-blind randomized clinical trial.
Mojdeh BahramrezaieFardin AmidiAshraf AleyasinAboTaleb SaremiMarzieh AghahoseiniSamaneh BrenjianMahshad KhodarahmianArash PooladiPublished in: Journal of assisted reproduction and genetics (2019)
Based on the results, resveratrol may improve some outcomes of PCOS patients, probably through changing the serum levels of some sex hormones and expression of VEGF & HIF1 genes in the angiogenesis pathway of granulosa cells.
Keyphrases
- polycystic ovary syndrome
- endothelial cells
- vascular endothelial growth factor
- induced apoptosis
- insulin resistance
- poor prognosis
- cell cycle arrest
- end stage renal disease
- chronic kidney disease
- genome wide
- newly diagnosed
- ejection fraction
- endoplasmic reticulum stress
- prognostic factors
- gene expression
- cell death
- peritoneal dialysis
- metabolic syndrome
- clinical trial
- type diabetes
- dna methylation
- skeletal muscle
- genome wide identification
- weight loss
- wound healing
- patient reported outcomes
- pi k akt