Use of proteomics to identify biomarkers associated with chronic kidney disease and long-term outcomes in patients with myocardial infarction.

Robert EdforsL LindhagenJ SpaakM EvansP AndellT BaronJ MörtbergM RezeliB SalzingerP LundmanK SzummerP TornvallH N WallénS H JacobsonT KahanG Marko-VargaD ErlingeS JamesB LindahlT Jernberg

Published in: Journal of internal medicine (2020)

In patients with MI, a proteomic approach could identify six biomarkers that best predicted CKD. These biomarkers were also amongst the most important predictors of long-term outcomes. Thus, these biomarkers indicate underlying mechanisms that may contribute to the poor prognosis seen in patients with MI and CKD.

Keyphrases

chronic kidney disease
poor prognosis
end stage renal disease
long non coding rna
heart failure
mass spectrometry
peritoneal dialysis