Association of psychological distress and DNA methylation: A 5-year longitudinal population-based twin study.

Xuanming HongKe MiaoWeihua CaoJun LvCanqing YuTao HuangDianjianyi SunChunxiao LiaoYuanjie PangRunhua HuZengchang PangMin YuHua WangXianping WuYu LiuWenjing GaoLiming Li

Published in: Psychiatry and clinical neurosciences (2023)

This study identified and validated PD-related CpG sites in Chinese twin population, and suggested that PD may be the cause of changes in DNAm over time. The findings provide new insights into the molecular mechanisms underlying PD pathophysiology. This article is protected by copyright. All rights reserved.

Keyphrases

dna methylation
gene expression
cross sectional
physical activity
sleep quality
copy number