Phosphorylation-Mediated Activation of β-Catenin-TCF4-CEGRs/ALCDs Pathway Is an Essential Event in Development of Aggressive Hepatoblastoma.

Ruhi Gulati Margaret A HanlonMaggie LutzTyler QuitmeyerJames GellerGregory TiaoLubov TimchenkoNikolai Timchenko

Published in: Cancers (2022)

The phosphorylation-mediated activation of the β-catenin-TCF4-p300-CEGRs/ALCDs pathway increases oncogene expression in patients with aggressive liver cancer and promotes the development of hepatoblastoma.

Keyphrases

epithelial mesenchymal transition
cell proliferation
poor prognosis
protein kinase
binding protein