First In-Human Medical Imaging with a PASylated 89Zr-Labeled Anti-HER2 Fab-Fragment in a Patient with Metastatic Breast Cancer.
Antonia RichterKarina KnorrMartin SchlapschyStephanie RobuVolker MorathClaudia MendlerHsi-Yu YenKatja SteigerMarion KiechleWolfgang WeberArne SkerraMarkus SchwaigerPublished in: Nuclear medicine and molecular imaging (2020)
This study demonstrates that a PASylated Fab tracer shows appropriate blood clearance to allow sensitive visualization of small tumor lesions in a clinical setting.