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Not Just an Anchor: The Human Filum Terminale Contains Stretch Sensitive and Nociceptive Nerve Endings and Responds to Electrical Stimulation With Paraspinal Muscle Activation.

Petra M KlingeAbigail McElroyOwen P LearyJohn E DonahueAndrew MumfordThomas BrinkerZiya L Gokaslan
Published in: Neurosurgery (2022)
Morphological and electrophysiological results indicate the presence of functional sensory nerve endings in the FT. Like other spine ligaments, the FT may serve as a proprioceptive element but may also contribute to back pain in spine disorders.
Keyphrases
  • endothelial cells
  • peripheral nerve
  • spinal cord injury
  • skeletal muscle
  • induced pluripotent stem cells
  • neuropathic pain
  • pluripotent stem cells
  • spinal cord