Mitochondrial oxygen consumption rate of human embryos declines with maternal age.

Naoharu MorimotoShu HashimotoMasaya YamanakaTatsuya NakanoManabu SatohYoshiharu NakaokaHisataka IwataAtsushi FukuiYoshiharu MorimotoHiroaki Shibahara

Published in: Journal of assisted reproduction and genetics (2020)

The data of the present study revealed that mitochondrial function at the morula stage of human embryos decreased with their maternal age and a decrease of mitochondrial function led to slow-paced development and impaired developmental rate from morulae to blastocysts.

Keyphrases

endothelial cells
birth weight
oxidative stress
pluripotent stem cells
pregnancy outcomes
electronic health record
body mass index
weight loss
weight gain
artificial intelligence