Exacerbations of Chronic Obstructive Pulmonary Disease and Cardiac Events. A Post Hoc Cohort Analysis from the SUMMIT Randomized Clinical Trial.
Ken M KunisakiMark T DransfieldJulie A AndersonRobert D BrookPeter M A CalverleyBartolome R CelliCourtney CrimBenjamin F HartleyFernando J MartinezDavid E NewbyAlexa A PragmanJørgen VestboJulie C YatesDennis E Niewoehnernull nullPublished in: American journal of respiratory and critical care medicine (2019)
In patients with COPD with CVD or risk factors for CVD, exacerbations confer an increased risk of subsequent CVD events, especially in hospitalized patients and within the first 30 days after exacerbation. Patients and clinicians should have heightened vigilance for early CVD events after AECOPD. Clinical trial registered with www.clinicaltrials.gov (NCT 01313676).
Keyphrases
- chronic obstructive pulmonary disease
- clinical trial
- end stage renal disease
- cystic fibrosis
- ejection fraction
- lung function
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- double blind
- palliative care
- left ventricular
- randomized controlled trial
- intensive care unit
- air pollution
- mechanical ventilation
- patient reported