Obesity and Baseline Estradiol Levels Are Independent Predictors for Initiation of Anastrozole in Hypogonadal Men on Clomiphene Citrate.
Sorena KeihaniNathan J AlderPhilip J ChengGregory J StoddardAlexander W PastuszakJames M HotalingPublished in: The world journal of men's health (2020)
In our practice, following CC monotherapy, 30% of men were initiated on CC+AZ. Obesity (BMI≥30 kg/m²) and baseline estradiol ≥18.5 pg/mL can predict the conversion to combination therapy with addition of AZ. This information can be used to counsel patients and also help to identify patients who can be started on combination therapy upfront.
Keyphrases
- combination therapy
- insulin resistance
- metabolic syndrome
- weight gain
- weight loss
- end stage renal disease
- type diabetes
- newly diagnosed
- high fat diet induced
- ejection fraction
- chronic kidney disease
- healthcare
- body mass index
- prognostic factors
- primary care
- estrogen receptor
- randomized controlled trial
- polycystic ovary syndrome
- replacement therapy
- health information
- patient reported outcomes
- adipose tissue
- patient reported