Implementation of test-and-treat with doxycycline and temephos ground larviciding as alternative strategies for accelerating onchocerciasis elimination in an area of loiasis co-endemicity: the COUNTDOWN consortium multi-disciplinary study protocol.
Samuel WanjiTheobald Mue NjiLouise HamillLaura DeanKim OzanoAbdel J NjouendouRaphael A AbongElisabeth Dibando ObieAndrew AmuamRelindis EkanyaWinston Patrick Chounna NdongmoBertrand L NdzeshangEbua Gallus FungDum-Buo NnamdiDesmond Akumtoh NkimbengSamuel TeghenEmmanuel KahHelen PiotrowskiArmelle ForrerJahangir A M KhanMaame E WoodeLouis NiessenVictoria WatsonZakariaou NjoumemiMichele E MurdochRachael ThomsonSally TheobaldPeter EnyongJoseph D TurnerMark J TaylorPublished in: Parasites & vectors (2019)
Using a multidisciplinary approach, we aim to assess the effectiveness of TTd, alone or in combination with ground larviciding, following a single intervention round and scrutinise the acceptability and feasibility of implementing at scale in similar hotspots of onchocerciasis infection, to accelerate onchocerciasis elimination.