Comparative efficacy of prolonged-release melatonin versus clonazepam for isolated rapid eye movement sleep behavior disorder.

Jung-Ick ByunYu Yong ShinYoon-Ah SeongSeon-Min YoonKyoung Jin HwangYu Jin JungKwang Su ChaKi-Young JungWon Chul Shin

Published in: Sleep & breathing = Schlaf & Atmung (2022)

Four weeks of clonazepam, but not PR melatonin, improved RWA. RBD symptom improvement tended to be better after clonazepam than PR melatonin in exchange for increased depressive symptoms and daytime sleepiness. ClinicalTrials.gov identifier: NCT03255642 (first submitted August 21, 2017).

Keyphrases

sleep quality
depressive symptoms
obstructive sleep apnea
social support
sleep apnea
positive airway pressure
gestational age
quantum dots