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Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults.

David MatuskeyJean-Dominique GallezotNabeel B NabulsiShannan HenryKristen TorresMark DiasGustavo A AngaritaYiyun HuangSusan E ShoafRichard E CarsonShailly Mehrotra
Published in: Journal of psychopharmacology (Oxford, England) (2022)
High occupancy at NET and moderate occupancy at DAT and SERT was observed at peak concentrations achieved following 400 mg total daily doses of centanafadine.
Keyphrases
  • open label
  • physical activity
  • high intensity
  • clinical trial
  • randomized controlled trial
  • placebo controlled