Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults.

David MatuskeyJean-Dominique Gallezot Nabeel B NabulsiShannan HenryKristen TorresMark DiasGustavo A AngaritaYiyun HuangSusan E ShoafRichard E CarsonShailly Mehrotra

Published in: Journal of psychopharmacology (Oxford, England) (2022)

High occupancy at NET and moderate occupancy at DAT and SERT was observed at peak concentrations achieved following 400 mg total daily doses of centanafadine.

Keyphrases

open label
physical activity
high intensity
clinical trial
randomized controlled trial
placebo controlled