Sugarcane cystatin CaneCPI-1 promotes osteogenic differentiation in human dental pulp cells: a new insight into cysteine proteases inhibitors.

Elisandra Marcia RodriguesK S ViolaA L Gomes-CornélioAndrea Soares-Costa Flavio Henrique-Silva Carlos Rossa Junior Juliane Maria Guerreiro-Tanomaru Mario Tanomaru-Filho

Published in: International endodontic journal (2020)

CaneCPI-1 was cytocompatible and also induced the differentiation of hDPCs in osteogenic phenotype in vitro. CaneCPI-1 is a promising molecule to induce pulp repair.

Keyphrases

mesenchymal stem cells
bone marrow
endothelial cells
induced apoptosis
high glucose
cell cycle arrest
diabetic rats
induced pluripotent stem cells
oxidative stress
drug induced
pluripotent stem cells
signaling pathway
single molecule