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Functional Connectivity Favors Aberrant Visual Network c-Fos Expression Accompanied by Cortical Synapse Loss in a Mouse Model of Alzheimer's Disease.

Oliver J L'EsperanceJoshua McGheeGarett DavidsonSuraj NiraulaAdam S SmithAlexandre A SosunovShirley Shidu YanJaichandar Subramanian
Published in: Journal of Alzheimer's disease : JAD (2024)
Visual network structural and functional disruptions are biased toward cortical regions in pre-plaque J20 mice, and the cellular and synaptic dysregulation in the AD-model represents a maladaptive modification of the baseline physiology seen in WT conditions.
Keyphrases
  • functional connectivity
  • resting state
  • mouse model
  • poor prognosis
  • coronary artery disease
  • cognitive decline
  • high fat diet induced
  • type diabetes
  • insulin resistance
  • wild type