High expression of the vacuole membrane protein 1 (VMP1) is a potential marker of poor prognosis in HER2 positive breast cancer.
Arsalan AmirfallahAdalgeir ArasonHjorleifur EinarssonEydis Thorunn GudmundsdottirEdda Sigridur FreysteinsdottirKristrun Audur OlafsdottirOskar Thor JohannssonBjarni Agnar AgnarssonRosa Bjork BarkardottirInga ReynisdottirPublished in: PloS one (2019)
The results suggest that high VMP1 expression is a potential marker of poor prognosis in HER2 positive BC. Further studies are needed to elucidate how VMP1 could affect pathways supportive of tumorigenesis.