Association of Blood Biomarkers of Inflammation With Acute Concussion in Collegiate Athletes and Military Service Academy Cadets.
Timothy B MeierDaniel L HuberBryna D GoecknerJessica M GillPaul F PasquinaSteven P BroglioThomas Walker McAllisterJaroslaw HarezlakMichael A McCreanull nullPublished in: Neurology (2023)
IL-6 and IL-1RA (male participants only) are elevated in the early-acute window postconcussion and may aid in diagnostic decisions beyond traditional blood markers and common clinical measures. IL-1RA results highlight sex differences in the immune response to concussion which should be considered in future biomarker work.