MARCO+ Macrophage Dynamics in Regenerating Liver after 70% Liver Resection in Mice.
Andrey V ElchaninovAnastasia LokhoninaPolina A VishnyakovaAnna G SobolevaAnastasiya PoltavetsDaria ArtemovaAndrey MakarovValeria GlinkinaDmitry GoldshteinGalina BolshakovaGennady SukhikhTimur Kh FatkhudinovPublished in: Biomedicines (2021)
The data indicate that the number of MARCO-positive macrophages in the regenerating liver increases due to the activation of MARCO synthesis in the liver macrophages. The increased expression of MARCO by macrophages can be regarded as a sign of their activation. In the present study, stimulation with LPS led to an increase in the expression of the Marco gene in both Kupffer cells and macrophages of bone marrow origin.
Keyphrases
- poor prognosis
- bone marrow
- induced apoptosis
- mesenchymal stem cells
- adipose tissue
- electronic health record
- binding protein
- genome wide
- gene expression
- dna methylation
- copy number
- long non coding rna
- cell proliferation
- signaling pathway
- anti inflammatory
- metabolic syndrome
- endoplasmic reticulum stress
- big data
- artificial intelligence