Association Between Statin Use and Depressive Symptoms in a Large Community-Dwelling Older Population Living in Australia and the USA: A Cross-Sectional Study.

Bruno AgustiniMohammadreza MohebbiRobyn L WoodsJohn J McNeilMark R NelsonRaj C ShahAnne M MurrayMichael E ErnstChristopher M ReidAndrew TonkinJessica E LockeryMichael Berknull null

Published in: CNS drugs (2020)

This study in a large community-dwelling older population did not show any association of statins with late-life depressive symptoms, after accounting for important socioeconomic and demographic factors. Confounding by indication is an important issue to be addressed in future pharmacoepidemiologic studies of statins.

Keyphrases

community dwelling
depressive symptoms
cardiovascular disease
social support
sleep quality
coronary artery disease
physical activity
risk factors