Efficacy and safety of fast-acting insulin aspart in comparison with insulin aspart in type 1 diabetes (onset 1): A 52-week, randomized, treat-to-target, phase III trial.
Chantal MathieuBruce W BodeEdward FranekAthena Philis-TsimikasLudger RoseTina GraungaardAnne Birk ØsterskovDavid Russell-JonesPublished in: Diabetes, obesity & metabolism (2018)
At 52 weeks, overall glycaemic control had significantly improved with faster aspart vs IAsp, consistent with the 26-week study findings. Achieving an insulin profile closer to physiological insulin secretion with faster aspart translates into lower PPG and HbA1c levels compared with those achieved with IAsp in people with T1D.