Surface expression of the immunotherapeutic target GD2 in osteosarcoma depends on cell confluency.
Malena WiebelSareetha KailayangiriBianca AltvaterJutta MeltzerKay GrobeSabine KupichClaudia RossigPublished in: Cancer reports (Hoboken, N.J.) (2021)
Expression of GD2 in OS cell lines is highly variable and associated with increasing cell confluency in vitro. Strategies for selective upregulation of GD2 are needed to enable effective therapeutic targeting of this antigen in OS.