Expression of HOXB7 in the Lung of Patients with Idiopathic Pulmonary Fibrosis: A Proof-of-Concept Study.

Anna Valeria SamarelliRoberto TonelliGiulia RaineriIlenia MastroliaMatteo CostantiniLuca FabbianiVirginia Catani Tiziana PetrachiGiulia BruzziDario AndrisaniFilippo GozziAlessandro Marchioni Valentina Masciale Beatrice AraminiValentina RuggieriGiulia GrisendiMassimo Dominici Stefania Cerri Enrico Maria Clini

Published in: Biomedicines (2024)

The expression of HOXB7 is higher in the lung of IPF patients compared to controls, and was represented in different cellular compartments within the lung niche. Further investigations are needed to clarify its role in the pathogenesis and progression of IPF.

Keyphrases

idiopathic pulmonary fibrosis
poor prognosis
end stage renal disease
interstitial lung disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
binding protein
prognostic factors
long non coding rna
patient reported