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PIGA Mutations and Glycosylphosphatidylinositol Anchor Dysregulation in Polyposis-Associated Duodenal Tumorigenesis.

Elena MeuserKyle ChangAngharad WaltersJoanna J HurleyHannah D WestIain PerryMatthew MortLaura Reyes-UribeRebekah TruscottNicholas JonesRachel LawrenceGareth J S JenkinsPeter J GilesSunil DolwaniBilal Al-SarirehNeil HawkesEmma L ShortGeraint T WilliamsMelissa W TaggartKim LuetchfordPatrick M LynchDiantha TerlouwMaartje NielsenSarah-Jane WaltonAndrew LatchfordSusan K ClarkJulian R SampsonEduardo VilarLaura E Thomas
Published in: Molecular cancer research : MCR (2024)
PIGA somatic mutation in duodenal tumors from patients with FAP and MAP and loss of membrane GPI-anchors may present new opportunities for understanding and intervention in duodenal tumorigenesis.
Keyphrases
  • randomized controlled trial
  • copy number
  • high density